Glucophage improves pregnancies and reduces miscarriages

Glucophage, also known as Metformin is an oral drug that is used by children and adults who suffer from type 2 diabetes. If affected individuals are unable to control their blood sugar by following a strict diet, exercising regularly and maintaining a healthy weight, their doctor may prescribe Glucophage.

Improved chance of pregnancy

A study of 48 women with Polycystic Ovary Syndrome - PCOS and infertility was conducted. They were first given metformin and 19 of them resumed menstruating and showed indications of ovulation. But 10 required clomiphene (a fertility drug) in addition to metformin in order to show evidence of ovulation. Twenty women of the 48 (42%) became pregnant.

Reduced risk of miscarriage

Another aspect of PCOS-related infertility is the tendency for repeated miscarriages. A study looked at 65 women who received Glucophage during their pregnancies vs. 31 who did not. The early pregnancy (first trimester) loss rate in the metformin group was 8.8% as compared to a 41.9% loss in the untreated group. Of those women who previously had miscarried, 11.1% of the metformin group miscarried again, while 58.3% of the untreated group again miscarried.